3K2P
HIV-1 Reverse Transcriptase Isolated RnaseH Domain with the Inhibitor beta-thujaplicinol Bound at the Active Site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Reverse Transcriptase | polymer | 136 | 14955.0 | 2 | UniProt (P03366) Pfam (PF00075) | Human immunodeficiency virus type 1 (HIV-1) | Reverse transcriptase/ribonuclease H, p66 RT |
| 2 | C, D, F, G (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 3 | E, H (A, B) | 2,7-dihydroxy-4-(propan-2-yl)cyclohepta-2,4,6-trien-1-one | non-polymer | 180.2 | 2 | Chemie (JTH) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence modifications
A, B: 427 - 560 (UniProt: P03366)
| PDB | External Database | Details |
|---|---|---|
| Ala 425 | - | expression tag |
| Leu 426 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29910.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 580.2 | |
| All* | Total formula weight | 30490.2 |
