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3JZS

Human MDM2 liganded with a 12mer peptide inhibitor (pDIQ)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase Mdm2polymer8610173.01UniProt (Q00987)
Pfam (PF02201)
Homo sapiens (human)p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2
2B
(P)
pDIQ peptide (12mer)polymer121563.71
3C
(P)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4D, E
(A, P)
waterwater18.055Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight11736.7
Non-Polymers*Number of molecules1
Total formula weight62.1
All*Total formula weight11798.8
*Water molecules are not included.

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PDB entries from 2025-07-30

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