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3JZR

Human MDM2 liganded with a 12mer peptide inhibitor (pDI6W)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase Mdm2polymer11012592.41UniProt (Q00987)
Pfam (PF02201)
Homo sapiens (human)p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2
2B
(P)
pDI6W peptide (12mer)polymer121519.71
3C, D
(A, P)
waterwater18.0116Chemie (HOH)
Sequence modifications
A: 17 - 125 (UniProt: Q00987)
PDBExternal DatabaseDetails
Gly 16-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight14112.1
All*Total formula weight14112.1
*Water molecules are not included.

227111

PDB entries from 2024-11-06

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