3JWE
Crystal structure of human mono-glyceride lipase in complex with SAR629
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | MGLL protein | polymer | 320 | 35292.5 | 2 | UniProt (Q6IBG9) Pfam (PF12146) UniProt (by SIFTS) (Q99685) | Homo sapiens (human) | Monoglyceride lipase, isoform CRA_b, cDNA, FLJ96595, Homo sapiens monoglyceride lipase (MGLL), mRNA |
| 2 | C, D, E (A, B) | 1-[bis(4-fluorophenyl)methyl]-4-(1H-1,2,4-triazol-1-ylcarbonyl)piperazine | non-polymer | 383.4 | 3 | Chemie (F4P) | |||
| 3 | F, G (A, B) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 313 (UniProt: Q6IBG9)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70585.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1150.2 | |
| All* | Total formula weight | 71735.2 |
