3JTL

Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Proteasome subunit alpha	polymer	227	25125.6	7	UniProt (P25156) Pfam (PF10584) Pfam (PF00227) In PDB	Thermoplasma acidophilum	Multicatalytic endopeptidase complex subunit alpha
2	H, I, J, K, L...	Proteasome subunit beta	polymer	203	22294.8	7	UniProt (P28061) Pfam (PF00227) In PDB	Thermoplasma acidophilum	Multicatalytic endopeptidase complex subunit beta
3	O, P, Q, R, S...	Proteasome activator protein PA26	polymer	228	25117.6	7	UniProt (Q9U8G2) Pfam (PF02252) In PDB	Trypanosoma brucei

Sequence modifications

O, P, Q, R, S, T, U: 4 - 231 (UniProt: Q9U8G2)

PDB	External Database	Details
Val 49	Thr 49	variant
His 225	Gly 225	engineered mutation
Leu 226	Ser 226	engineered mutation
Val 228	His 228	engineered mutation
Leu 229	Met 229	engineered mutation
Tyr 230	Val 230	engineered mutation
Arg 231	Ser 231	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	21
	Total formula weight	507766.6
All*	Total formula weight	507766.6

*Water molecules are not included.