3JSF

Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor 638 at 1.93a resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Macrophage migration inhibitory factor	polymer	122	13426.2	3	UniProt (P14174) Pfam (PF01187) In PDB	Homo sapiens (human)	MIF, Phenylpyruvate tautomerase, L-dopachrome tautomerase, L-dopachrome isomerase, Glycosylation-inhibiting factor, GIF
2	A, B, C	7-(2-fluorobenzyl)quinolin-8-ol	non-polymer		253.3	3	Chemie (XV1)
3	B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4		water	water		18.0	152	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 114 (UniProt: P14174)

PDB	External Database	Details
Leu 115	-	expression tag
Glu 116	-	expression tag
His 117	-	expression tag
His 118	-	expression tag
His 119	-	expression tag
His 120	-	expression tag
His 121	-	expression tag
His 122	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	40278.6
Non-Polymers*	Number of molecules	5
	Total formula weight	951.9
All*	Total formula weight	41230.6

*Water molecules are not included.