3JAP
Structure of a partial yeast 48S preinitiation complex in closed conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | Met-tRNAi (U31:A39 variant) | polymer | 75 | 24223.5 | 1 | Kluyveromyces lactis | ||
| 2 | B (2) | 18S rRNA | polymer | 1781 | 573814.1 | 1 | Kluyveromyces lactis | ||
| 3 | C (3) | mRNA | polymer | 25 | 7786.6 | 1 | synthetic construct | ||
| 4 | D (A) | uS2 | polymer | 254 | 28264.5 | 1 | UniProt (Q6CN12) Pfam (PF00318) | Kluyveromyces lactis | |
| 5 | E (B) | eS1 | polymer | 255 | 28971.6 | 1 | UniProt (Q6CWD0) Pfam (PF01015) | Kluyveromyces lactis | |
| 6 | F (C) | uS5 | polymer | 259 | 27650.0 | 1 | UniProt (Q6CKL3) Pfam (PF00333) Pfam (PF03719) | Kluyveromyces lactis | |
| 7 | G (D) | uS3 | polymer | 237 | 26300.5 | 1 | UniProt (Q6CRK7) Pfam (PF07650) Pfam (PF00189) | Kluyveromyces lactis | |
| 8 | H (E) | eS4 | polymer | 261 | 29617.5 | 1 | UniProt (Q6CWJ2) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) Pfam (PF08071) Pfam (PF01479) | Kluyveromyces lactis | |
| 9 | I (F) | uS7 | polymer | 227 | 25386.0 | 1 | UniProt (Q6CRA3) Pfam (PF00177) | Kluyveromyces lactis | |
| 10 | J (G) | eS6 | polymer | 236 | 26970.4 | 1 | UniProt (Q6CM04) Pfam (PF01092) | Kluyveromyces lactis | |
| 11 | K (H) | eS7 | polymer | 190 | 21735.3 | 1 | UniProt (Q6CTD6) Pfam (PF01251) | Kluyveromyces lactis | |
| 12 | L (I) | eS8 | polymer | 201 | 22642.7 | 1 | UniProt (Q6CMG3) Pfam (PF01201) | Kluyveromyces lactis | |
| 13 | M (J) | uS4 | polymer | 188 | 21587.0 | 1 | UniProt (Q6CM18) Pfam (PF00163) Pfam (PF01479) | Kluyveromyces lactis | |
| 14 | N (K) | eS10 | polymer | 106 | 12584.4 | 1 | UniProt (Q6CVZ5) Pfam (PF03501) | Kluyveromyces lactis | |
| 15 | O (L) | uS17 | polymer | 156 | 17843.9 | 1 | UniProt (Q6CX80) Pfam (PF16205) Pfam (PF00366) | Kluyveromyces lactis | |
| 16 | P (M) | eS12 | polymer | 134 | 14466.4 | 1 | UniProt (Q6CLU4) Pfam (PF01248) | Kluyveromyces lactis | |
| 17 | Q (N) | uS15 | polymer | 151 | 16989.9 | 1 | UniProt (Q6CJK0) Pfam (PF08069) Pfam (PF00312) | Kluyveromyces lactis | |
| 18 | R (O) | uS11 | polymer | 137 | 14530.7 | 1 | UniProt (P27069) Pfam (PF00411) | Kluyveromyces lactis | |
| 19 | S (P) | uS19 | polymer | 142 | 15986.8 | 1 | UniProt (Q6CKV4) Pfam (PF00203) | Kluyveromyces lactis | |
| 20 | T (Q) | uS9 | polymer | 143 | 15874.5 | 1 | UniProt (Q875N2) Pfam (PF00380) | Kluyveromyces lactis | |
| 21 | U (R) | eS17 | polymer | 136 | 15722.2 | 1 | UniProt (Q6CWU3) Pfam (PF00833) | Kluyveromyces lactis | |
| 22 | V (S) | uS13 | polymer | 146 | 17084.6 | 1 | UniProt (Q6CWT9) Pfam (PF00416) | Kluyveromyces lactis | |
| 23 | W (T) | eS19 | polymer | 144 | 15879.0 | 1 | UniProt (Q6CXM0) Pfam (PF01090) | Kluyveromyces lactis | |
| 24 | X (U) | uS10 | polymer | 117 | 13337.6 | 1 | UniProt (Q6CIM1) Pfam (PF00338) | Kluyveromyces lactis | |
| 25 | Y (V) | eS21 | polymer | 87 | 9797.9 | 1 | UniProt (Q6CXT6) Pfam (PF01249) | Kluyveromyces lactis | |
| 26 | Z (W) | uS8 | polymer | 130 | 14645.0 | 1 | UniProt (Q6CW21) Pfam (PF00410) | Kluyveromyces lactis | |
| 27 | AA (X) | uS12 | polymer | 145 | 16047.9 | 1 | UniProt (F2Z602) Pfam (PF00164) | Kluyveromyces lactis | |
| 28 | BA (Y) | eS24 | polymer | 135 | 15194.5 | 1 | UniProt (Q6CU44) Pfam (PF01282) | Kluyveromyces lactis | |
| 29 | CA (Z) | eS25 | polymer | 108 | 12002.1 | 1 | UniProt (Q6CW78) Pfam (PF03297) | Kluyveromyces lactis | |
| 30 | DA (a) | eS26 | polymer | 119 | 13540.0 | 1 | UniProt (Q6CS01) Pfam (PF01283) | Kluyveromyces lactis | |
| 31 | EA (b) | eS27 | polymer | 82 | 8884.4 | 1 | UniProt (Q6CNL2) Pfam (PF01667) | Kluyveromyces lactis | |
| 32 | FA (c) | eS28 | polymer | 67 | 7549.8 | 1 | UniProt (P33285) Pfam (PF01200) | Kluyveromyces lactis | |
| 33 | GA (d) | uS14 | polymer | 56 | 6662.6 | 1 | UniProt (Q6CPG3) Pfam (PF00253) | Kluyveromyces lactis | |
| 34 | HA (e) | eS30 | polymer | 63 | 7141.4 | 1 | UniProt (Q6CUH5) Pfam (PF04758) | Kluyveromyces lactis | |
| 35 | IA (f) | eS31 | polymer | 150 | 17111.0 | 1 | UniProt (P69061) Pfam (PF00240) Pfam (PF01599) | Kluyveromyces lactis | |
| 36 | JA (g) | RACK1 | polymer | 326 | 35830.9 | 1 | UniProt (Q6CNI7) Pfam (PF00400) | Kluyveromyces lactis | |
| 37 | KA (h) | eL41 | polymer | 25 | 3354.2 | 1 | UniProt (P0CX86) Pfam (PF05162) | Kluyveromyces lactis | |
| 38 | LA (i) | eIF1A | polymer | 153 | 17462.2 | 1 | UniProt (P38912) Pfam (PF01176) | Saccharomyces cerevisiae (yeast) | |
| 39 | MA (j) | eIF2 alpha | polymer | 304 | 34763.7 | 1 | UniProt (P20459) Pfam (PF00575) Pfam (PF07541) | Saccharomyces cerevisiae (yeast) | |
| 40 | NA (k) | eIF2 gamma | polymer | 527 | 57942.7 | 1 | UniProt (P32481) Pfam (PF00009) Pfam (PF03144) Pfam (PF09173) | Saccharomyces cerevisiae (yeast) | |
| 41 | OA (l) | eIF2 beta | polymer | 285 | 31631.3 | 1 | UniProt (P09064) Pfam (PF01873) | Saccharomyces cerevisiae (yeast) | |
| 42 | PA (m) | eIF1 | polymer | 108 | 12330.1 | 1 | UniProt (P32911) Pfam (PF01253) | Saccharomyces cerevisiae (yeast) | |
| 43 | QA (o) | eIF3a | polymer | 588 | 64752.1 | 1 | UniProt (P38249) Pfam (PF22591) | Saccharomyces cerevisiae (yeast) | |
| 44 | RA (p) | eIF3c | polymer | 652 | 73397.4 | 1 | UniProt (P32497) Pfam (PF05470) Pfam (PF01399) | Saccharomyces cerevisiae (yeast) | |
| 45 | SA (q) | eIF3i | polymer | 347 | 38803.4 | 1 | UniProt (P40217) Pfam (PF00400) | Saccharomyces cerevisiae (yeast) | |
| 46 | TA (r) | eIF3b | polymer | 31 | 3963.6 | 1 | UniProt (P06103) | Saccharomyces cerevisiae (yeast) | |
| 47 | UA (s) | eIF3g | polymer | 52 | 5942.6 | 1 | UniProt (A6ZZ25) Pfam (PF12353) | Saccharomyces cerevisiae (yeast) | |
| 48 | AB, AC, AD, BB, BC... (2, k) | MAGNESIUM ION | non-polymer | 24.3 | 81 | Chemie (MG) | |||
| 49 | DE, XD, YD, ZD (l, a, b, f) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 50 | AE (k) | METHIONINE | non-polymer | 149.2 | 1 | Chemie (MET) | |||
| 51 | CE (k) | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | non-polymer | 521.2 | 1 | Chemie (GCP) |
Sequence modifications
o: 1 - 495 (UniProt: P38249)
p: 193 - 206 (UniProt: P32497)
p: 251 - 812 (UniProt: P32497)
o: 1 - 866 (PDB: 3JAP)
p: 20 - 812 (PDB: 3JAP)
p: 193 - 206 (UniProt: P32497)
p: 251 - 812 (UniProt: P32497)
o: 1 - 866 (PDB: 3JAP)
p: 20 - 812 (PDB: 3JAP)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 47 |
| Total formula weight | 1544000.6 | |
| Non-Polymers* | Number of molecules | 87 |
| Total formula weight | 2900.8 | |
| All* | Total formula weight | 1546901.4 |
