3J8X

High-resolution structure of no-nucleotide kinesin on microtubules

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (K)	Kinesin-1 heavy chain	polymer	349	39238.1	1	UniProt (P33176) Pfam (PF00225)	Homo sapiens (human)	Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain, UKHC
2	B (A)	Tubulin alpha-1B chain	polymer	451	50204.4	1	UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (pig)	Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain
3	C (B)	Tubulin beta-2B chain	polymer	445	49983.8	1	UniProt (F2Z5B2)	Sus scrofa (pig)
4	D (A)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	1	Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466)
5	E (B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537)

Sequence modifications

K: 1 - 349 (UniProt: P33176)

PDB	External Database	Details
Ser 7	Cys 7	conflict
Ala 168	Cys 168	conflict
Ser 174	Cys 174	conflict
Ser 330	Cys 330	conflict

B: 1 - 455 (UniProt: F2Z5B2)

PDB	External Database	Details
Ser 203	Cys 201	conflict

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	139426.4
Non-Polymers*	Number of molecules	2
	Total formula weight	966.4
All*	Total formula weight	140392.8

*Water molecules are not included.