3J8F
Cryo-EM reconstruction of poliovirus-receptor complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | Capsid protein VP1 | polymer | 302 | 33488.6 | 1 | UniProt (P03300) Pfam (PF00073) | Human poliovirus 1 Mahoney | P1D, Virion protein 1 |
| 2 | B (2) | Capsid protein VP2 | polymer | 272 | 30075.8 | 1 | UniProt (P03300) Pfam (PF00073) | Human poliovirus 1 Mahoney | P1B, Virion protein 2 |
| 3 | C (3) | Capsid protein VP3 | polymer | 238 | 26547.5 | 1 | UniProt (P03300) Pfam (PF00073) | Human poliovirus 1 Mahoney | P1C, Virion protein 3 |
| 4 | D (4) | Capsid protein VP4 | polymer | 69 | 7603.4 | 1 | UniProt (P03300) Pfam (PF02226) | Human poliovirus 1 Mahoney | P1A, Virion protein 4 |
| 5 | E (7) | Poliovirus receptor | polymer | 423 | 46168.2 | 1 | UniProt (P15151) Pfam (PF07686) Pfam (PF08205) | Homo sapiens (human) | PVR/CD155, Nectin-like protein 5, NECL-5 |
| 6 | F, J (A, E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 7 | G (B) | beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G51347YJ) | |||
| 8 | H, I (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 9 | K (F) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 10 | L (7) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
3: 1 - 238 (UniProt: P03300)
4: 2 - 69 (UniProt: P03300)
7: 1 - 417 (UniProt: P15151)
| PDB | External Database | Details |
|---|---|---|
| Ser 123 | Phe 464 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Myr 1 | - | modified residue |
| PDB | External Database | Details |
|---|---|---|
| His 418 | - | expression tag |
| His 419 | - | expression tag |
| His 420 | - | expression tag |
| His 421 | - | expression tag |
| His 422 | - | expression tag |
| His 423 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 143883.5 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 3649.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 147754.1 |
