3J5Q
Structure of TRPV1 ion channel in complex with DkTx and RTX determined by single particle electron cryo-microscopy
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | D, B, E, G | Transient receptor potential cation channel subfamily V member 1 | polymer | 628 | 70795.2 | 4 | UniProt (O35433) Pfam (PF00023) Pfam (PF00520) In PDB | Rattus norvegicus (Norway rat) | TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1,Vanilloid receptor type 1-like |
2 | A, C, F, H | Kappa-theraphotoxin-Cg1a 1 | polymer | 31 | 3433.0 | 4 | UniProt (P0C247) Pfam (PF07740) In PDB | Chilobrachys guangxiensis | double-knot toxin |
Sequence modifications
D, B, E, G: 111 - 719 (UniProt: O35433)
D, B, E, G: 721 - 762 (PDB: 3J5Q)
PDB | External Database | Details |
---|---|---|
- | Asn 604 | deletion |
- | Asn 605 | deletion |
- | Ser 606 | deletion |
- | Leu 607 | deletion |
- | Pro 608 | deletion |
- | Met 609 | deletion |
- | Glu 610 | deletion |
- | Ser 611 | deletion |
- | Thr 612 | deletion |
- | Pro 613 | deletion |
- | His 614 | deletion |
- | Lys 615 | deletion |
- | Cys 616 | deletion |
- | Arg 617 | deletion |
- | Gly 618 | deletion |
- | Ser 619 | deletion |
- | Ala 620 | deletion |
- | Cys 621 | deletion |
- | Lys 622 | deletion |
- | Pro 623 | deletion |
- | Gly 624 | deletion |
- | Asn 625 | deletion |
- | Ser 626 | deletion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 296912.9 | |
All* | Total formula weight | 296912.9 |