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3J0K

Orientation of RNA polymerase II within the human VP16-Mediator-pol II-TFIIF assembly

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA-directed RNA polymerase II largest subunitpolymer1455163180.01Pfam (PF04997)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Pfam (PF04992)
Pfam (PF04990)
UniProt (by SIFTS) (P04050)
Homo sapiens (human)
2B
(B)
DNA-directed RNA polymerase II 140 kDa polypeptidepolymer1224138937.31Pfam (PF04565)
Pfam (PF04566)
Pfam (PF04567)
Pfam (PF00562)
Pfam (PF04560)
Pfam (PF04563)
Pfam (PF04561)
UniProt (by SIFTS) (P08518)
Homo sapiens (human)
3C
(C)
DNA-directed RNA polymerase II 45 kDa polypeptidepolymer26830140.11Pfam (PF01193)
Pfam (PF01000)
UniProt (by SIFTS) (P16370)
Homo sapiens (human)
4D
(D)
DNA-directed RNA polymerase II 32 kDa polypeptidepolymer22125451.21Pfam (PF03874)
UniProt (by SIFTS) (P20433)
Homo sapiens (human)
5E
(E)
DNA-directed RNA polymerases I, II, and III 27 kDa polypeptidepolymer21525117.11Pfam (PF03871)
Pfam (PF01191)
UniProt (by SIFTS) (P20434)
Homo sapiens (human)
6F
(F)
DNA-directed RNA polymerases I, II, and III 23 kDa polypeptidepolymer849675.21Pfam (PF01192)
UniProt (by SIFTS) (P20435)
Homo sapiens (human)
7G
(G)
DNA-directed RNA polymerase II 19 kDa polypeptidepolymer17119081.11Pfam (PF03876)
Pfam (PF00575)
UniProt (by SIFTS) (P34087)
Homo sapiens (human)
8H
(H)
DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptidepolymer14616525.41Pfam (PF03870)
UniProt (by SIFTS) (P20436)
Homo sapiens (human)
9I
(I)
DNA-directed RNA polymerase II subunit 9polymer12214308.21Pfam (PF02150)
Pfam (PF01096)
UniProt (by SIFTS) (P27999)
Homo sapiens (human)
10J
(J)
DNA-directed RNA polymerases I/II/III subunit 10polymer708290.71Pfam (PF01194)
UniProt (by SIFTS) (P22139)
Homo sapiens (human)
11K
(K)
DNA-directed RNA polymerase II 13.6 kDa polypeptidepolymer12013633.51Pfam (PF13656)
UniProt (by SIFTS) (P38902)
Homo sapiens (human)
12L
(L)
DNA-directed RNA polymerases I, II, and III 7.7 kDa polypeptidepolymer465252.31Homo sapiens (human)
13M
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
14N, O, P, Q, R...
(A, B, C, I, J...)
ZINC IONnon-polymer65.49Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight469592.0
Non-Polymers*Number of molecules10
Total formula weight613.0
All*Total formula weight470204.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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