3IXP
Crystal structure of the ecdysone receptor bound to BYI08346
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Gene regulation protein | polymer | 263 | 29951.8 | 1 | UniProt (Q7SIF6) Pfam (PF00104) In PDB | Heliothis virescens (Tobacco budworm moth) | |
2 | D | Ecdysone receptor | polymer | 265 | 30206.6 | 1 | UniProt (B9UCQ4) Pfam (PF00104) In PDB | Helicoverpa armigera (American bollworm corn ear worm scarce bordered straw tobacco budworm) | |
3 | A | L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE | non-polymer | 709.9 | 1 | Chemie (EPH) | |||
4 | D | N-[2-(2-chlorophenyl)-4-methyl-5-(1-methylethyl)-1H-imidazol-1-yl]-5-methyl-2,3-dihydro-1,4-benzodioxine-6-carboxamide | non-polymer | 425.9 | 1 | Chemie (834) | |||
5 | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
A: 205 - 466 (UniProt: Q7SIF6)
D: 285 - 532 (UniProt: B9UCQ4)
PDB | External Database | Details |
---|---|---|
Met 204 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 268 | - | expression tag |
Ser 269 | - | expression tag |
His 270 | - | expression tag |
Met 271 | - | expression tag |
Ala 272 | - | expression tag |
Ser 273 | - | expression tag |
Met 274 | - | expression tag |
Thr 275 | - | expression tag |
Gly 276 | - | expression tag |
Gly 277 | - | expression tag |
Gln 278 | - | expression tag |
Gln 279 | - | expression tag |
Met 280 | - | expression tag |
Gly 281 | - | expression tag |
Arg 282 | - | expression tag |
Asp 283 | - | expression tag |
Pro 284 | - | expression tag |
Tyr 303 | Trp 303 | engineered mutation |
Ser 361 | Ala 361 | engineered mutation |
Ser 456 | Leu 456 | engineered mutation |
Ser 483 | Cys 483 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 60158.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1135.8 | |
All* | Total formula weight | 61294.2 |