3IXP
Crystal structure of the ecdysone receptor bound to BYI08346
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003707 | molecular_function | nuclear steroid receptor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0030518 | biological_process | nuclear receptor-mediated steroid hormone signaling pathway |
| D | 0003677 | molecular_function | DNA binding |
| D | 0004879 | molecular_function | nuclear receptor activity |
| D | 0005634 | cellular_component | nucleus |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0035076 | biological_process | ecdysone receptor signaling pathway |
| D | 0035100 | molecular_function | ecdysone binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE EPH A 900 |
| Chain | Residue |
| A | LEU230 |
| A | ALA339 |
| A | GLY340 |
| A | ILE344 |
| A | SER431 |
| A | LEU435 |
| A | PHE438 |
| A | LEU440 |
| A | HOH993 |
| A | VAL238 |
| A | PRO239 |
| A | PHE242 |
| A | LEU249 |
| A | CYS250 |
| A | GLY328 |
| A | LEU331 |
| A | GLN338 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 834 D 800 |
| Chain | Residue |
| D | THR343 |
| D | MET380 |
| D | MET381 |
| D | VAL384 |
| D | TYR408 |
| D | MET413 |
| D | VAL416 |
| D | LEU420 |
| D | GLN503 |
| D | ASN504 |
| D | MET507 |
| D | LEU522 |
