3IXH
X-ray crystal structure of the extended-spectrum AmpC Y221G mutant beta-lactamase in complex with cefotaxime at 2.3 Angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Beta-lactamase | polymer | 358 | 39481.8 | 2 | UniProt (P00811) Pfam (PF00144) | Escherichia coli | Cephalosporinase |
| 2 | C (B) | CEFOTAXIME, C3' cleaved, open, bound form | non-polymer | 397.4 | 1 | Chemie (CEF) | |||
| 3 | D, E (B, A) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
B, A: 4 - 361 (UniProt: P00811)
| PDB | External Database | Details |
|---|---|---|
| Gly 221 | Tyr 237 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78963.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 397.4 | |
| All* | Total formula weight | 79361.0 |
