3IWU
Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | 5-hydroxyisourate hydrolase | polymer | 138 | 15399.6 | 8 | UniProt (Q06S87) Pfam (PF00576) | Danio rerio (Zebrafish) | HIU hydrolase, HIUHase, Transthyretin-related protein |
| 2 | I, J, K, L, M... (A, B, C, D, E...) | water | water | 18.0 | 636 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: -18 - 119 (UniProt: Q06S87)
| PDB | External Database | Details |
|---|---|---|
| Ala 16 | Ile 35 | engineered mutation |
| Thr 116 | Tyr 135 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 123196.6 | |
| All* | Total formula weight | 123196.6 |
