3IWM

The octameric SARS-CoV main protease

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	3C-like proteinase	polymer	306	33876.6	4	UniProt (P0C6U8) Pfam (PF05409) UniProt (by SIFTS) (P0C6X7)	SARS coronavirus (SARS-CoV)	3CL-PRO, 3CLp
2	E, F, G, H (H, F, G, E)	N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE	polymer	6	680.8	4	BIRD (PRD_002214)	synthetic construct

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	138229.7
All*	Total formula weight	138229.7

*Water molecules are not included.