3IV2
Crystal structure of mature apo-Cathepsin L C25A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Cathepsin L1 | polymer | 220 | 24159.6 | 2 | UniProt (P07711) Pfam (PF00112) In PDB | Homo sapiens (human) | Major excreted protein, MEP, Cathepsin L1 heavy chain and Cathepsin L1 light chain |
| 2 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 3 | A, B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 4 | A, B | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | water | water | 18.0 | 78 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 220 (UniProt: P07711)
| PDB | External Database | Details |
|---|---|---|
| Ala 25 | Cys 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48319.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1088.9 | |
| All* | Total formula weight | 49408.2 |
