3IU2
Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90096
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glycylpeptide N-tetradecanoyltransferase 1 | polymer | 383 | 44541.3 | 2 | UniProt (P30419) Pfam (PF01233) Pfam (PF02799) In PDB | Homo sapiens (human) | Peptide N-myristoyltransferase 1, Myristoyl-CoA:protein N-myristoyltransferase 1, NMT 1, Type I N-myristoyltransferase |
| 2 | A, B | TETRADECANOYL-COA | non-polymer | 977.9 | 2 | Chemie (MYA) | |||
| 3 | A, B | (2R)-2-{4-hydroxy-5-methoxy-2-[3-(4-methylpiperazin-1-yl)propyl]phenyl}-3-pyridin-3-yl-1,3-thiazolidin-4-one | non-polymer | 442.6 | 2 | Chemie (096) | |||
| 4 | water | water | 18.0 | 695 | Chemie (HOH) |
Sequence modifications
A, B: 115 - 496 (UniProt: P30419)
| PDB | External Database | Details |
|---|---|---|
| Gly 114 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 89082.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2840.9 | |
| All* | Total formula weight | 91923.6 |
