3ISN
Crystal structure of HIV-1 RT bound to A 6-vinylpyrimidine inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Reverse transcriptase/ribonuclease H | polymer | 560 | 64516.0 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) | Human immunodeficiency virus (HIV-1) | HIV-1 reverse transcriptase, p66 RT |
| 2 | B (D) | p51 RT | polymer | 427 | 49927.4 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) | Human immunodeficiency virus (HIV-1) | |
| 3 | C (C) | 6-ethenyl-N,N-dimethyl-2-(methylsulfonyl)pyrimidin-4-amine | non-polymer | 227.3 | 1 | Chemie (EDM) | |||
| 4 | D, E (C, D) | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence modifications
C: 1 - 560 (UniProt: P03366)
| PDB | External Database | Details |
|---|---|---|
| Gln 478 | Glu 1077 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 114443.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 227.3 | |
| All* | Total formula weight | 114670.7 |
