3IS5

Crystal structure of CDPK kinase domain from toxoplasma Gondii, TGME49_018720

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Calcium-dependent protein kinase	polymer	285	32605.2	6	UniProt (B6KS23)	Toxoplasma gondii
2	AA, G, L, O, R... (F, A, B, C, D...)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	6	Chemie (ANP)
3	H, P, Y (A, C, F)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
4	BA, I, K, N, S... (F, A, B, D, E)	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
5	J, M, Q, U, X... (A, B, C, D, E...)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
6	CA, DA, EA, FA, GA... (A, B, C, D, E...)	water	water		18.0	154	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 130 - 396 (UniProt: B6KS23)

PDB	External Database	Details
Met 112	-	expression tag
His 113	-	expression tag
His 114	-	expression tag
His 115	-	expression tag
His 116	-	expression tag
His 117	-	expression tag
His 118	-	expression tag
Ser 119	-	expression tag
Ser 120	-	expression tag
Gly 121	-	expression tag
Arg 122	-	expression tag
Glu 123	-	expression tag
Asn 124	-	expression tag
Leu 125	-	expression tag
Tyr 126	-	expression tag
Phe 127	-	expression tag
Gln 128	-	expression tag
Gly 129	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	195631.5
Non-Polymers*	Number of molecules	22
	Total formula weight	3947.9
All*	Total formula weight	199579.4

*Water molecules are not included.