3IOL
Crystal structure of Glucagon-Like Peptide-1 in complex with the extracellular domain of the Glucagon-Like Peptide-1 Receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glucagon-like peptide 1 receptor | polymer | 126 | 14739.3 | 1 | UniProt (P43220) Pfam (PF02793) | Homo sapiens (human) | GLP-1 receptor, GLP-1-R, GLP-1R |
| 2 | B (B) | Glucagon | polymer | 31 | 3359.7 | 1 | UniProt (P01275) Pfam (PF00123) | Homo sapiens | GLP-1, Glucagon-like peptide 1, Glicentin, Glicentin-related polypeptide |
| 3 | C (A) | decyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside | non-polymer | 498.6 | 1 | Chemie (10M) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence modifications
A: 24 - 145 (UniProt: P43220)
| PDB | External Database | Details |
|---|---|---|
| Gly 20 | - | expression tag |
| Ser 21 | - | expression tag |
| His 22 | - | expression tag |
| Met 23 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 18099.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 498.6 | |
| All* | Total formula weight | 18597.6 |
