3IOL

Crystal structure of Glucagon-Like Peptide-1 in complex with the extracellular domain of the Glucagon-Like Peptide-1 Receptor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004930	molecular_function	G protein-coupled receptor activity
A	0004967	molecular_function	glucagon receptor activity
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0008528	molecular_function	G protein-coupled peptide receptor activity
A	0016020	cellular_component	membrane
B	0005179	molecular_function	hormone activity
B	0005576	cellular_component	extracellular region

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE 10M A 1

Chain	Residue
A	TYR101
A	LEU111
A	ASP114
A	TRP120
A	ASP122
B	THR13
B	VAL16
B	SER17

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Functional Information from PROSITE/UniProt

site_id	PS00260
Number of Residues	23
Details	GLUCAGON Glucagon / GIP / secretin / VIP family signature. HAEGTFtSDVssylegqaAKEFI

Chain	Residue	Details
B	HIS7-ILE29

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site_id	PS00649
Number of Residues	25
Details	G_PROTEIN_RECEP_F2_1 G-protein coupled receptors family 2 signature 1. CnrtFDeya.CWpdGepgsfvnvsCP

Chain	Residue	Details
A	CYS62-PRO86

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P55095

Chain	Residue	Details
B	SER14
B	SER17

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Arginine amide => ECO:0000269|PubMed:2753890

Chain	Residue	Details
B	ARG36
A	GLU128

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site_id	SWS_FT_FI3
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:22412906

Chain	Residue	Details
A	ASN63
A	ASN82
A	ASN115

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