3IOH
Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histo-blood group ABO system transferase | polymer | 298 | 34654.0 | 1 | UniProt (P16442) Pfam (PF03414) | Homo sapiens (human) | NAGAT, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Histo-blood group A transferase, A transferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Fucosylglycoprotein 3-alpha-galactosyltransferase, Histo-blood group B transferase, B transferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | water | water | 18.0 | 379 | Chemie (HOH) |
Sequence modifications
A: 64 - 354 (UniProt: P16442)
| PDB | External Database | Details |
|---|---|---|
| Met 57 | - | expression tag |
| Ala 58 | - | expression tag |
| Ile 59 | - | expression tag |
| Gly 60 | - | expression tag |
| Glu 61 | - | expression tag |
| Phe 62 | - | expression tag |
| Met 63 | - | expression tag |
| Gly 266 | Leu 266 | engineered mutation |
| Ala 268 | Gly 268 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34654.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 34746.1 |
