3IO8

BimL12F in complex with Bcl-xL

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Bcl-2-like protein 1	polymer	158	17918.0	2	UniProt (Q07817) Pfam (PF02180) Pfam (PF00452)	Homo sapiens (human)	Bcl2-L-1, Apoptosis regulator Bcl-X
2	B, D (B, D)	Bcl-2-like protein 11	polymer	26	3308.7	2	UniProt (O43521) Pfam (PF08945)	Homo sapiens	Bcl2-L-11, Bcl2-interacting mediator of cell death
3	E, F, G (A, C)	ZINC ION	non-polymer		65.4	3	Chemie (ZN)
4	H, I, J, K (A, B, C, D)	water	water		18.0	29	Chemie (HOH)

Sequence modifications

A, C: 1 - 26 (UniProt: Q07817)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

A, C: 83 - 209 (UniProt: Q07817)
B, D: 51 - 76 (UniProt: O43521)

PDB	External Database	Details
Phe 62	Leu 152	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	42453.3
Non-Polymers*	Number of molecules	3
	Total formula weight	196.2
All*	Total formula weight	42649.6

*Water molecules are not included.