3INV
Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase COMPLEXED WITH NADPH, dUMP AND C-448 ANTIFOLATE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Bifunctional dihydrofolate reductase-thymidylate synthase | polymer | 521 | 58928.1 | 2 | UniProt (Q27793) Pfam (PF00186) Pfam (PF00303) In PDB | Trypanosoma cruzi | DHFR-TS, Dihydrofolate reductase, Thymidylate synthase |
| 2 | A, B | 1-[3-(2,3-dichlorophenoxy)propoxy]-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine | non-polymer | 360.2 | 2 | Chemie (C50) | |||
| 3 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 4 | A, B | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 2 | Chemie (UMP) | |||
| 5 | A, B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 315 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 117856.2 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3288.2 | |
| All* | Total formula weight | 121144.4 |
