3IM4
Crystal structure of cAMP-dependent Protein Kinase A Regulatory Subunit I alpha in complex with dual-specific A-Kinase Anchoring Protein 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | cAMP-dependent protein kinase type I-alpha regulatory subunit | polymer | 50 | 6006.0 | 2 | UniProt (P00514) Pfam (PF02197) | Bos taurus (bovine) | |
| 2 | C (C) | Dual specificity A kinase-anchoring protein 2 | polymer | 45 | 5086.7 | 1 | UniProt (O43572) | Homo sapiens (human) | Kinase anchor protein 10, Protein kinase A-anchoring protein 10, PRKA10, D-AKAP-2 |
| 3 | D, E, F, G, H (A, B) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 4 | I, J, K (A, B, C) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
C: 623 - 662 (UniProt: O43572)
| PDB | External Database | Details |
|---|---|---|
| Gly 618 | - | expression tag |
| Ser 619 | - | expression tag |
| Pro 620 | - | expression tag |
| Glu 621 | - | expression tag |
| Phe 622 | - | expression tag |
| Val 646 | Ile 646 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 17098.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 327.0 | |
| All* | Total formula weight | 17425.7 |
