3IL4
Structure of E. faecalis FabH in complex with acetyl CoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | polymer | 320 | 35119.7 | 4 | UniProt (Q820T1) Pfam (PF08545) Pfam (PF08541) | Enterococcus faecalis | 3-oxoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III |
| 2 | E, F, G, H (A, B, C, D) | ACETYL COENZYME *A | non-polymer | 809.6 | 4 | Chemie (ACO) PubChem (25210474) PubChem (444493) PubChem (24860528) PubChem (44141873) PubChem (45254004) PubChem (53393727) PubChem (56846401) PubChem (53245716) PubChem (181) PubChem (6302) PubChem (87656764) PubChem (6917106) PubChem (91746285) PubChem (10079099) PubChem (87656765) PubChem (89102998) PubChem (11987898) PubChem (16061174) PubChem (6857822) PubChem (134956084) PubChem (124511019) PubChem (124931617) PubChem (129274027) PubChem (154496096) PubChem (162968672) PubChem (170108977) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 6 - 325 (UniProt: Q820T1)
| PDB | External Database | Details |
|---|---|---|
| Thr 192 | Ala 188 | engineered mutation |
| Ser 253 | Asn 249 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 140478.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 3238.3 | |
| All* | Total formula weight | 143716.9 |
