3IHJ

Human alanine aminotransferase 2 in complex with PLP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Alanine aminotransferase 2	polymer	498	55405.3	1	UniProt (Q8TD30) Pfam (PF00155)	Homo sapiens (human)	ALT2, Glutamic-pyruvic transaminase 2, Glutamate pyruvate transaminase 2, GPT 2, Glutamic-alanine transaminase 2
2	B (A)	PYRIDOXAL-5'-PHOSPHATE	non-polymer		247.1	1	Chemie (PLP)
3	C, D (A)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	E (A)	water	water		18.0	93	Chemie (HOH)

Sequence modifications

A: 49 - 523 (UniProt: Q8TD30)

PDB	External Database	Details
Met 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
His 29	-	expression tag
His 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
Ser 33	-	expression tag
Ser 34	-	expression tag
Gly 35	-	expression tag
Val 36	-	expression tag
Asp 37	-	expression tag
Leu 38	-	expression tag
Gly 39	-	expression tag
Thr 40	-	expression tag
Glu 41	-	expression tag
Asn 42	-	expression tag
Leu 43	-	expression tag
Tyr 44	-	expression tag
Phe 45	-	expression tag
Gln 46	-	expression tag
Ser 47	-	expression tag
Met 48	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	55405.3
Non-Polymers*	Number of molecules	3
	Total formula weight	437.1
All*	Total formula weight	55842.4

*Water molecules are not included.