3IFA
Human muscle fructose-1,6-bisphosphatase E69Q mutant in complex with AMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Fructose-1,6-bisphosphatase isozyme 2 | polymer | 338 | 36665.9 | 4 | UniProt (O00757) Pfam (PF00316) Pfam (PF18913) | Homo sapiens (human) | FBPase 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase 2 |
| 2 | E, M, R, W (A, B, C, D) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 4 | Chemie (AMP) PubChem (224) PubChem (34768) PubChem (83862) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (5316444) PubChem (5742864) PubChem (12163610) PubChem (12358355) PubChem (16397049) PubChem (16760266) PubChem (40467049) PubChem (40469468) PubChem (44348067) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (46875232) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (92144436) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (12358354) PubChem (122197642) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 3 | F, G, H, I, N... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
| 4 | AA, J, K, L, Q... (D, A, B, C) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) PubChem (753) | |||
| 5 | BA, CA, DA, EA (A, B, C, D) | water | water | 18.0 | 650 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 338 (UniProt: O00757)
| PDB | External Database | Details |
|---|---|---|
| Gln 69 | Glu 70 | engineered mutation |
| Leu 85 | Val 86 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 146663.6 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 3190.3 | |
| All* | Total formula weight | 149853.9 |
