3IBJ
X-ray structure of PDE2A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | cGMP-dependent 3',5'-cyclic phosphodiesterase | polymer | 691 | 78952.3 | 2 | UniProt (O00408) Pfam (PF01590) Pfam (PF00233) | Homo sapiens (human) | Cyclic GMP-stimulated phosphodiesterase, CGS-PDE, cGSPDE |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 191 | Chemie (HOH) |
Sequence modifications
A, B: 215 - 900 (UniProt: O00408)
| PDB | External Database | Details |
|---|---|---|
| Met 214 | - | initiating methionine |
| Leu 901 | - | expression tag |
| Val 902 | - | expression tag |
| Pro 903 | - | expression tag |
| Arg 904 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 157904.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 179.4 | |
| All* | Total formula weight | 158084.0 |
