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3I80

Protein Tyrosine Phosphatase 1B - Transition state analog for the second catalytic step

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase non-receptor type 1polymer32137365.61UniProt (P18031)
Pfam (PF00102)
Homo sapiens (human)Protein-tyrosine phosphatase 1B, PTP-1B
2B
(A)
VANADATE IONnon-polymer114.91Chemie (VO4)
3C
(A)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.11Chemie (TRS)
4D, E, F
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
5G
(A)
waterwater18.0231Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37365.6
Non-Polymers*Number of molecules5
Total formula weight513.4
All*Total formula weight37879.0
*Water molecules are not included.

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PDB entries from 2026-01-14

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