3I6W
Structure and Activation Mechanism of the CHK2 DNA-Damage Checkpoint Kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Serine/threonine-protein kinase Chk2 | polymer | 443 | 50839.9 | 8 | UniProt (O96017) Pfam (PF00498) Pfam (PF00069) | Homo sapiens (human) | Cds1 |
Sequence modifications
A, B, C, D, E, F, G, H: 70 - 512 (UniProt: O96017)
| PDB | External Database | Details |
|---|---|---|
| Arg 249 | Lys 249 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 406719.6 | |
| All* | Total formula weight | 406719.6 |
