3I5K

Crystal structure of the NS5B polymerase from Hepatitis C Virus (HCV) strain JFH1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	RNA-directed RNA polymerase	polymer	566	62972.3	4	UniProt (Q99IB8) Pfam (PF00998)	Hepatitis C virus JFH-1 (HCV)	NS5B, p68
2	E, F, G, H, I... (A, B, C, D)	PHOSPHATE ION	non-polymer		95.0	17	Chemie (PO4)
3	V, W, X, Y (A, B, C, D)	water	water		18.0	1800	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 565 (UniProt: Q99IB8)

PDB	External Database	Details
Val 566	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	251889.0
Non-Polymers*	Number of molecules	17
	Total formula weight	1614.5
All*	Total formula weight	253503.5

*Water molecules are not included.