3I4U

Crystal Structure Analysis of a helicase associated domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	ATP-dependent RNA helicase DHX8	polymer	270	31208.0	1	UniProt (Q14562) Pfam (PF04408) Pfam (PF21010) Pfam (PF07717) In PDB	Homo sapiens (Human)	DEAH box protein 8, RNA helicase HRH1
2	A	BROMIDE ION	non-polymer		79.9	3	Chemie (BR)
3	A	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
4		water	water		18.0	190	Chemie (HOH)

Sequence modifications

A: 950 - 1183 (UniProt: Q14562)

PDB	External Database	Details
Met 935	-	expression tag
Gly 936	-	expression tag
Asp 937	-	expression tag
Arg 938	-	expression tag
Gly 939	-	expression tag
Pro 940	-	expression tag
Glu 941	-	expression tag
Phe 942	-	expression tag
Glu 943	-	expression tag
Leu 944	-	expression tag
Gly 945	-	expression tag
Thr 946	-	expression tag
Arg 947	-	expression tag
Gly 948	-	expression tag
Ser 949	-	expression tag
Leu 1184	-	expression tag
Glu 1185	-	expression tag
Val 1186	-	expression tag
Asp 1187	-	expression tag
Leu 1188	-	expression tag
Gln 1189	-	expression tag
Gly 1190	-	expression tag
Asp 1191	-	expression tag
His 1192	-	expression tag
Gly 1193	-	expression tag
Leu 1194	-	expression tag
Ser 1195	-	expression tag
Ala 1196	-	expression tag
Trp 1197	-	expression tag
Ser 1198	-	expression tag
His 1199	-	expression tag
Pro 1200	-	expression tag
Gln 1201	-	expression tag
Phe 1202	-	expression tag
Glu 1203	-	expression tag
Lys 1204	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	31208.0
Non-Polymers*	Number of molecules	10
	Total formula weight	884.4
All*	Total formula weight	32092.4

*Water molecules are not included.