3HZG

Crystal structure of mycobacterium tuberculosis thymidylate synthase X bound with FAD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Thymidylate synthase thyX	polymer	258	28699.4	4	UniProt (P66930) Pfam (PF02511) UniProt (by SIFTS) (P9WG57)	Mycobacterium tuberculosis	TS, TSase
2	E, F, I, J, K... (A, B, C, D)	PHOSPHATE ION	non-polymer		95.0	9	Chemie (PO4)
3	G, L, O, T (A, B, C, D)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	4	Chemie (FAD)
4	H, P, Q (A, C)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5	U, V, W, X (A, B, C, D)	water	water		18.0	257	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 250 (UniProt: P66930)

PDB	External Database	Details
Leu 251	-	expression tag
Glu 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag
His 256	-	expression tag
His 257	-	expression tag
His 258	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	114797.7
Non-Polymers*	Number of molecules	16
	Total formula weight	4273.2
All*	Total formula weight	119070.9

*Water molecules are not included.