3HZF
Structure of TR-alfa bound to selective thyromimetic GC-1 in C2 space group
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thyroid hormone receptor, alpha isoform 1 variant | polymer | 269 | 31006.2 | 1 | UniProt (Q59FW3) Pfam (PF00104) UniProt (by SIFTS) (P10827) | Homo sapiens (human) | |
| 2 | B (A) | {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid | non-polymer | 328.4 | 1 | Chemie (B72) | |||
| 3 | C (A) | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A: 148 - 410 (UniProt: Q59FW3)
| PDB | External Database | Details |
|---|---|---|
| Ala 142 | - | expression tag |
| Arg 143 | - | expression tag |
| Gly 144 | - | expression tag |
| Ser 145 | - | expression tag |
| His 146 | - | expression tag |
| Met 147 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31006.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 328.4 | |
| All* | Total formula weight | 31334.6 |
