3HY0
Crystal Structure of catalytic fragment of E. coli AlaRS G237A in complex with GlySA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Alanyl-tRNA synthetase | polymer | 441 | 49938.1 | 2 | UniProt (P00957) Pfam (PF01411) In PDB | Escherichia coli | Alanine-tRNA ligase, AlaRS |
2 | A, B | 5'-O-(glycylsulfamoyl)adenosine | non-polymer | 403.4 | 2 | Chemie (G5A) | |||
3 | A, B | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
4 | A, B | 2-HYDROXYETHYL DISULFIDE | non-polymer | 154.3 | 4 | Chemie (HED) | |||
5 | water | water | 18.0 | 1187 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 441 (UniProt: P00957)
PDB | External Database | Details |
---|---|---|
Leu 104 | His 105 | engineered mutation |
Leu 108 | Gln 109 | engineered mutation |
Leu 112 | Glu 113 | engineered mutation |
Ala 237 | Gly 238 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 99876.2 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1900.4 | |
All* | Total formula weight | 101776.5 |