3HY0
Crystal Structure of catalytic fragment of E. coli AlaRS G237A in complex with GlySA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004813 | molecular_function | alanine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006419 | biological_process | alanyl-tRNA aminoacylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004813 | molecular_function | alanine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006419 | biological_process | alanyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE G5A A 442 |
| Chain | Residue |
| A | ARG69 |
| A | GLU209 |
| A | ILE210 |
| A | ASN212 |
| A | ASP235 |
| A | ALA237 |
| A | GLY239 |
| A | ARG242 |
| A | HOH449 |
| A | HOH472 |
| A | HOH783 |
| A | ASP76 |
| A | HOH851 |
| A | ARG85 |
| A | HIS86 |
| A | HIS87 |
| A | PHE90 |
| A | MET92 |
| A | TRP170 |
| A | GLU183 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE EPE A 443 |
| Chain | Residue |
| A | LYS124 |
| A | GLU125 |
| A | ARG152 |
| A | HOH484 |
| A | HOH501 |
| A | HOH575 |
| A | HOH723 |
| A | HOH837 |
| A | HOH973 |
| B | SER25 |
| B | ARG66 |
| B | GLU346 |
| B | ASP347 |
| B | HOH812 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HED A 444 |
| Chain | Residue |
| A | ARG60 |
| A | ASP105 |
| A | PHE109 |
| A | HOH710 |
| A | HOH824 |
| A | HOH1005 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HED A 445 |
| Chain | Residue |
| A | PRO34 |
| A | HOH814 |
| A | HOH857 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE G5A B 442 |
| Chain | Residue |
| B | ARG69 |
| B | ASP76 |
| B | ARG85 |
| B | HIS86 |
| B | HIS87 |
| B | PHE90 |
| B | MET92 |
| B | TRP170 |
| B | GLU183 |
| B | GLU209 |
| B | ILE210 |
| B | ASN212 |
| B | ASP235 |
| B | ALA237 |
| B | GLY239 |
| B | ARG242 |
| B | HOH468 |
| B | HOH496 |
| B | HOH763 |
| B | HOH856 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE EPE B 443 |
| Chain | Residue |
| A | ALA24 |
| A | SER25 |
| A | ARG66 |
| A | GLU346 |
| A | ASP347 |
| A | HOH840 |
| A | HOH1121 |
| B | LYS124 |
| B | GLU125 |
| B | PRO149 |
| B | ARG152 |
| B | HOH495 |
| B | HOH563 |
| B | HOH798 |
| B | HOH955 |
| B | HOH1008 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE HED B 444 |
| Chain | Residue |
| B | ARG60 |
| B | ASP100 |
| B | TYR101 |
| B | PHE109 |
| B | ARG396 |
| B | ARG434 |
| B | HOH806 |
| B | HOH1165 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HED B 445 |
| Chain | Residue |
| B | PRO34 |
| B | HOH772 |
| B | HOH807 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"18723842","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30274179","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
