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3HXO

Crystal Structure of Von Willebrand Factor (VWF) A1 Domain in Complex with DNA Aptamer ARC1172, an Inhibitor of VWF-Platelet Binding

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
von Willebrand factorpolymer20923889.61UniProt (P04275)
Pfam (PF00092)
Homo sapiens (human)vWF, von Willebrand antigen 2, von Willebrand antigen II
2B
(B)
Aptamer ARC1172polymer4212884.21
3C, D
(A, B)
waterwater18.0177Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight36773.8
All*Total formula weight36773.8
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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