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3HXM

Structure of an argonaute complexed with guide DNA and target RNA duplex containing two mismatches.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Argonautepolymer68576728.71UniProt (Q746M7)
Pfam (PF22472)
Pfam (PF18309)
Pfam (PF22474)
Thermus thermophilus
2B
(C)
DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3')polymer216588.31
3C
(Y)
RNA (5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*UP*CP*AP*CP*UP*AP*CP*CP*UP*CP*GP*U)-3')polymer206248.81
4D
(C)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight89565.8
Non-Polymers*Number of molecules1
Total formula weight24.3
All*Total formula weight89590.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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