3HWR

Crystal structure of PanE/ApbA family ketopantoate reductase (YP_299159.1) from Ralstonia eutropha JMP134 at 2.15 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	2-dehydropantoate 2-reductase	polymer	318	34405.9	2	UniProt (Q46RB9) Pfam (PF02558) Pfam (PF08546) In PDB	Ralstonia eutropha	PanE/ApbA family ketopantoate reductase
2	A, B	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	2	Chemie (NDP)
3	A, B	BICINE	non-polymer		163.2	2	Chemie (BCN)
4	A, B	(4R)-2-METHYLPENTANE-2,4-DIOL	non-polymer		118.2	2	Chemie (MRD)
5		water	water		18.0	213	Chemie (HOH)

Sequence modifications

A, B: 1 - 299 (UniProt: Q46RB9)

PDB	External Database	Details
Mse -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Asp -15	-	expression tag
Lys -14	-	expression tag
Ile -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
Arg 244	Gly 244	see remark 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	68811.8
Non-Polymers*	Number of molecules	6
	Total formula weight	2053.5
All*	Total formula weight	70865.4

*Water molecules are not included.