3HWN
CATHEPSIN L with AZ13010160
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cathepsin L1 | polymer | 258 | 28678.8 | 4 | UniProt (P07711) Pfam (PF00112) | Homo sapiens (human) | Major excreted protein, MEP, Cathepsin L1 heavy chain, Cathepsin L1 light chain |
| 2 | E, F, G, H (A, B, C, D) | Nalpha-[(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)carbonyl]-N-[(2E)-2-iminoethyl]-3-{5-[(Z)-iminomethyl]-1,3,4-oxadiazol-2-yl}-L-phenylalaninamide | non-polymer | 464.5 | 4 | Chemie (BD3) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B, C, D: -37 - 220 (UniProt: P07711)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Thr 223 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 114715.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1858.1 | |
| All* | Total formula weight | 116573.3 |
