3HVR

Crystal structure of T. thermophilus Argonaute complexed with DNA guide strand and 19-nt RNA target strand with two Mg2+ at the cleavage site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Argonaute	polymer	685	76728.7	2	UniProt (Q746M7) Pfam (PF22472) Pfam (PF18309) Pfam (PF22474)	Thermus thermophilus
2	C, D (C, M)	5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*TP*GP*AP*TP*AP*GP*T)-3'	polymer	21	6588.3	2
3	E, F (D, N)	5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3'	polymer	19	5942.6	2
4	G, H, I, K, L... (A, B)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
5	J, N (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	178519.2
Non-Polymers*	Number of molecules	8
	Total formula weight	335.8
All*	Total formula weight	178854.9

*Water molecules are not included.