3HUG

Crystal structure of Mycobacterium tuberculosis anti-sigma factor RslA in complex with -35 promoter binding domain of sigL

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I...	RNA polymerase sigma factor	polymer	92	10249.4	10	UniProt (Q7D9D4) Pfam (PF04545) UniProt (by SIFTS) (P9WGH5) In PDB	Mycobacterium tuberculosis
2	B, D, F, H, J...	PROBABLE CONSERVED MEMBRANE PROTEIN	polymer	108	11334.8	10	UniProt (Q7D9D3) Pfam (PF13490) UniProt (by SIFTS) (P9WJ67) In PDB	Mycobacterium tuberculosis	Putative uncharacterized protein
3	I, L, M, P, Q...	SULFATE ION	non-polymer		96.1	10	Chemie (SO4)
4	H, J, L, N, P...	ZINC ION	non-polymer		65.4	10	Chemie (ZN)
5		water	water		18.0	269	Chemie (HOH)

Sequence modifications

A, C, E, G, I, K, M, O, Q, S: 99 - 177 (UniProt: Q7D9D4)

PDB	External Database	Details
Met 86	-	expression tag
Gly 87	-	expression tag
Ser 88	-	expression tag
Ser 89	-	expression tag
His 90	-	expression tag
His 91	-	expression tag
His 92	-	expression tag
His 93	-	expression tag
His 94	-	expression tag
His 95	-	expression tag
Ser 96	-	expression tag
Gln 97	-	expression tag
Asp 98	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	20
	Total formula weight	215841.8
Non-Polymers*	Number of molecules	20
	Total formula weight	1614.7
All*	Total formula weight	217456.5

*Water molecules are not included.