3HUG

Crystal structure of Mycobacterium tuberculosis anti-sigma factor RslA in complex with -35 promoter binding domain of sigL

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006352	biological_process	DNA-templated transcription initiation
A	0006355	biological_process	regulation of DNA-templated transcription
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006352	biological_process	DNA-templated transcription initiation
C	0006355	biological_process	regulation of DNA-templated transcription
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0006352	biological_process	DNA-templated transcription initiation
E	0006355	biological_process	regulation of DNA-templated transcription
G	0003700	molecular_function	DNA-binding transcription factor activity
G	0006352	biological_process	DNA-templated transcription initiation
G	0006355	biological_process	regulation of DNA-templated transcription
I	0003700	molecular_function	DNA-binding transcription factor activity
I	0006352	biological_process	DNA-templated transcription initiation
I	0006355	biological_process	regulation of DNA-templated transcription
K	0003700	molecular_function	DNA-binding transcription factor activity
K	0006352	biological_process	DNA-templated transcription initiation
K	0006355	biological_process	regulation of DNA-templated transcription
M	0003700	molecular_function	DNA-binding transcription factor activity
M	0006352	biological_process	DNA-templated transcription initiation
M	0006355	biological_process	regulation of DNA-templated transcription
O	0003700	molecular_function	DNA-binding transcription factor activity
O	0006352	biological_process	DNA-templated transcription initiation
O	0006355	biological_process	regulation of DNA-templated transcription
Q	0003700	molecular_function	DNA-binding transcription factor activity
Q	0006352	biological_process	DNA-templated transcription initiation
Q	0006355	biological_process	regulation of DNA-templated transcription
S	0003700	molecular_function	DNA-binding transcription factor activity
S	0006352	biological_process	DNA-templated transcription initiation
S	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 Q 1

Chain	Residue
I	GLN101
I	SER102
Q	HOH27
Q	ARG137
R	ARG76

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 L 109

Chain	Residue
L	ARG76
C	GLN101
C	SER102
K	GLN132
K	ARG137

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 3

Chain	Residue
A	GLN132
A	ARG137
B	ARG76
B	ALA80

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 M 4

Chain	Residue
M	GLN132
M	ARG137
N	ARG76

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 5

Chain	Residue
C	GLN132
C	ARG137
C	HOH183
D	ARG76

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 G 6

Chain	Residue
G	GLN132
G	ARG137
H	ARG76
H	ALA80

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 S 7

Chain	Residue
S	GLN132
S	ARG137
T	ARG76

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 P 109

Chain	Residue
O	ARG137
P	ARG76
P	ALA80

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 I 9

Chain	Residue
I	GLN132
I	ARG137
J	ARG76
Q	GLN101
Q	SER102

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 I 10

Chain	Residue
I	ARG113
I	LEU114
Q	ARG113
Q	LEU114
Q	ALA117
R	LEU74

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 109

Chain	Residue
B	HIS25
B	HIS50
B	CYS54
B	CYS57

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 109

Chain	Residue
D	HIS25
D	HIS50
D	CYS54
D	CYS57

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 109

Chain	Residue
F	HIS25
F	HIS50
F	CYS54
F	CYS57

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN H 109

Chain	Residue
H	HIS25
H	HIS50
H	CYS54
H	CYS57

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN J 109

Chain	Residue
J	HIS25
J	HIS50
J	CYS54
J	CYS57

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN L 110

Chain	Residue
L	HIS25
L	HIS50
L	CYS54
L	CYS57

---

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN N 109

Chain	Residue
N	HIS25
N	HIS50
N	CYS54
N	CYS57

---

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN P 110

Chain	Residue
P	HIS25
P	HIS50
P	CYS54
P	CYS57

---

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN R 109

Chain	Residue
R	HIS25
R	HIS50
R	CYS54
R	CYS57

---

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN T 109

Chain	Residue
T	HIS25
T	HIS50
T	CYS54
T	CYS57

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	BINDING: BINDING => ECO:0000269|PubMed:20184899

Chain	Residue	Details
B	HIS25
F	HIS50
F	CYS54
F	CYS57
H	HIS25
H	HIS50
H	CYS54
H	CYS57
J	HIS25
J	HIS50
J	CYS54
B	HIS50
J	CYS57
L	HIS25
L	HIS50
L	CYS54
L	CYS57
N	HIS25
N	HIS50
N	CYS54
N	CYS57
P	HIS25
B	CYS54
P	HIS50
P	CYS54
P	CYS57
R	HIS25
R	HIS50
R	CYS54
R	CYS57
T	HIS25
T	HIS50
T	CYS54
B	CYS57
T	CYS57
D	HIS25
D	HIS50
D	CYS54
D	CYS57
F	HIS25

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