Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3HUB

Human p38 MAP Kinase in Complex with Scios-469

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AMitogen-activated protein kinase 14polymer36041235.01UniProt (Q16539)
Pfam (PF00069)
In PDB
Homo sapiens (human)Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A
2Aoctyl beta-D-glucopyranosidenon-polymer292.41Chemie (BOG)
3A2-(6-chloro-5-{[(2R,5S)-4-(4-fluorobenzyl)-2,5-dimethylpiperazin-1-yl]carbonyl}-1-methyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamidenon-polymer513.01Chemie (469)
4waterwater18.096Chemie (HOH)
Sequence modifications
A: 2 - 360 (UniProt: Q16539)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ser 119Cys 119engineered mutation
Ser 162Cys 162engineered mutation
Cys 172Ala 172engineered mutation
Leu 327Phe 327engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41235.0
Non-Polymers*Number of molecules2
Total formula weight805.4
All*Total formula weight42040.3
*Water molecules are not included.

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon