3HTU

Crystal structure of the human VPS25-VPS20 subcomplex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G	Vacuolar protein-sorting-associated protein 25	polymer	79	9024.9	4	UniProt (Q9BRG1) Pfam (PF05871) In PDB	Homo sapiens (human)	hVps25, ESCRT-II complex subunit VPS25, ELL-associated protein of 20 kDa, Dermal papilla-derived protein 9
2	B, D, F, H	Vacuolar protein-sorting-associated protein 20	polymer	39	4704.4	4	UniProt (Q96FZ7) In PDB	Homo sapiens (human)	Chromatin-modifying protein 6, Charged multivesicular body protein 6, Vps20, hVps20
3		water	water		18.0	213	Chemie (HOH)

Sequence modifications

A, C, E, G: 102 - 176 (UniProt: Q9BRG1)

PDB	External Database	Details
Gly 98	-	expression tag
Ala 99	-	expression tag
Met 100	-	expression tag
Gly 101	-	expression tag

B, D, F, H: 11 - 48 (UniProt: Q96FZ7)

PDB	External Database	Details
Gly 10	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	54917.3
All*	Total formula weight	54917.3

*Water molecules are not included.