3HOC
Structure of the actin-binding domain of human filamin A mutant E254K
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Filamin-A | polymer | 272 | 30502.7 | 2 | UniProt (P21333) Pfam (PF00307) | Homo sapiens (human) | Alpha-filamin, Filamin-1, Endothelial actin-binding protein, Actin-binding protein 280, ABP-280, Non-muscle filamin |
| 2 | C, D, E, F (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 3 | G, H (A, B) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 269 (UniProt: P21333)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Met 0 | - | expression tag |
| Ala 1 | - | expression tag |
| Lys 254 | Glu 254 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61005.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 379.9 | |
| All* | Total formula weight | 61385.4 |
