3HNG
Crystal structure of VEGFR1 in complex with N-(4-Chlorophenyl)-2-((pyridin-4-ylmethyl)amino)benzamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vascular endothelial growth factor receptor 1 | polymer | 360 | 41081.1 | 1 | UniProt (P17948) Pfam (PF07714) | Homo sapiens (human) | VEGFR-1, Vascular permeability factor receptor, Tyrosine-protein kinase receptor FLT, Flt-1, Tyrosine-protein kinase FRT, Fms-like tyrosine kinase 1 |
| 2 | B (A) | N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide | non-polymer | 337.8 | 1 | Chemie (8ST) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 801 - 1158 (UniProt: P17948)
| PDB | External Database | Details |
|---|---|---|
| Ser 799 | - | expression tag |
| Met 800 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41081.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 373.3 | |
| All* | Total formula weight | 41454.4 |
