3HLL
Crystal Structure of Human p38alpha complexed with PH-797804
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 14 | polymer | 360 | 41343.2 | 1 | UniProt (Q16539) Pfam (PF00069) | Homo sapiens (human) | Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A |
| 2 | B (A) | 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamide | non-polymer | 477.3 | 1 | Chemie (I45) | |||
| 3 | C (A) | 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine | non-polymer | 257.2 | 1 | Chemie (I46) | |||
| 4 | D (A) | HYPOPHOSPHITE | non-polymer | 63.0 | 1 | Chemie (PO2) | |||
| 5 | E (A) | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41343.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 797.5 | |
| All* | Total formula weight | 42140.7 |
